Image 1-Blistering lesions along the lower limb.

Image 2 -Low power (100x) magnification demonstrates mild epidermal hyperplasia.

Image 3-Higher magnification (200x) demonstrates scattered dyskeratotic keratinocytes.

Image 4-Highest magnification (400x) demonstrating the dyskeratotic keratinocytes with minimal accompanying inflammatory cell infiltrate.

Image 5-Highest magnification demonstrating scattered melanophages.

What is your diagnosis?


Case Study

This is a 2 week old girl who presented with unilateral blistering lesions on the extremities. A punch biopsy is taken from the lower leg.

First Posted June 3, 2008

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