This is a 47 year old man who presents with a scaly nodule on the shoulder.
Cystic (Inverted) Warty Dyskeratoma
Warty dyskeratomas are relatively common epithelial lesions characterized by invaginated cup-shaped cyst with an extensive keratotic and parakeratotic plug. Characteristically there is suprabasilar acantholysis with papillary fronds and numerous acantholytic cells with dyskeratosis forming corp ronds and corp grains. This recent paper cited below describes several histological variants including tumors which may exhibit follicular differentiation. PCR analysis for HPV DNA was negative in all cases, distinguishing it from verruca vulgaris and cystic verruca.
Warty Dyskeratoma and other Acanthomas
Last Updated November 10, 2002
Send Emails to Webmaster at DermpathMD
Read the Medical Disclaimer